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Updated: May 6, 2026

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マウスモデルにおける有効なタウ免疫療法には,サイトソリック抗体受容体 TRIM21 が必要である

Aamir S Mukadam1,2, Lauren V C Miller1,2, Annabel E Smith1,2

  • 1UK Dementia Research Institute at the University of Cambridge, Cambridge CB2 0AH, UK.

Science (New York, N.Y.)
|March 30, 2023
PubMed
まとめ

タウ病理を標的とする抗体は,細胞塩基受容体TRIM21 (T21) を介して有効である. このメカニズムはニューロンのタウの蓄積を防ぐことで神経変性疾患の進行を防ぎます.

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