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Updated: Aug 4, 2025

Investigating Aortic Valve Calcification via Isolation and Culture of T Lymphocytes using Feeder Cells from Irradiated Buffy Coat
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Investigating Aortic Valve Calcification via Isolation and Culture of T Lymphocytes using Feeder Cells from Irradiated Buffy Coat

Published on: February 4, 2021

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トールのような受容体3は,保存されたカルシフィケーションのメカニズムを通じて大動脈狭窄を媒介する

Can Gollmann-Tepeköylü1, Michael Graber1, Jakob Hirsch1

  • 1Department of Cardiac Surgery (C.G.-T., M.G, J.H., S.M., L.P., F.N., E.K., N.F., D. Lobenwein, V.S., J.E., M.G., J.H.), Medical University of Innsbruck, Austria.

Circulation
|April 4, 2023
PubMed
まとめ

トール型受容体3 (TLR3) は,大動脈弁の化を調節する. ビグリカン (BGN) はTLR3を活性化させ,弁細胞の骨形成を促進し,動脈弁疾患 (CAVD) に寄与する.

キーワード:
トール型受容体3大動脈弁の病気ビグリカン細胞外マトリックスオステオゲネシスタンパク質

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