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Updated: Aug 4, 2025

Author Spotlight: Exploring the Role of Ion Channels in Cancer: Characterization and Potential Treatment Approaches
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Author Spotlight: Exploring the Role of Ion Channels in Cancer: Characterization and Potential Treatment Approaches

Published on: June 16, 2023

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ベンゾヒドラジドベースの人工イオンチャネル,がん細胞における塩化イオン濃度を調節し,オートファギーの障害によってアポトーシスを誘導する

Abhishek Mondal1, Shreyada N Save2, Susmita Sarkar3

  • 1Department of Chemistry, Indian Institute of Science Education and Research Pune, Dr. Homi Bhabha Road, Pashan, Pune 411008, Maharashtra, India.

Journal of the American Chemical Society
|April 6, 2023
PubMed
まとめ

新しいベンゾイルベンゾヒドラジド (1c) がナノチャネルに自己組み立てられ,選択的に塩化物イオンを輸送し,癌細胞でアポトーシスを誘発する. この人工的なイオンチャネルは 細胞の恒常性や自己消化を妨害し 癌でない細胞を救います

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