関連する実験動画

Updated: Aug 4, 2025

Analysis of LINE-1 Retrotransposition at the Single Nucleus Level
11:52

Analysis of LINE-1 Retrotransposition at the Single Nucleus Level

Published on: April 23, 2016

8.4K

ターゲット・プライム・リバース・トランスクリプションを誘発するR2非LTRの構造

Max E Wilkinson1,2,3,4,5, Chris J Frangieh1,2,3,4,5,6, Rhiannon K Macrae1,2,3,4,5

  • 1Howard Hughes Medical Institute, Cambridge, MA 02139, USA.

Science (New York, N.Y.)
|April 6, 2023
PubMed
まとめ

研究者は,標的型逆転写 (TPRT) を開始するBombyx mori R2の構造を視覚化しました. これはLINEのような非LTRレトロトランポゾンが DNAに遺伝物質を挿入する方法を示しています

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RNA Next-Generation Sequencing and a Bioinformatics Pipeline to Identify Expressed LINE-1s at the Locus-Specific Level11:04

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Determining 3'-Termini and Sequences of Nascent Single-Stranded Viral DNA Molecules during HIV-1 Reverse Transcription in Infected Cells13:07

Determining 3'-Termini and Sequences of Nascent Single-Stranded Viral DNA Molecules during HIV-1 Reverse Transcription in Infected Cells

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LTR retrotransposons are class I transposable elements with long terminal repeats flanking an internal coding region. These elements are less abundant in mammals compared to other class I transposable elements. About 8 percent of human genomic DNA comprises LTR retrotransposons. Some of the common examples of LTR retrotransposons are Ty elements in yeast and Copia elements in Drosophila.
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