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Updated: Aug 3, 2025

Constructing Cyclic Peptides Using an On-Tether Sulfonium Center
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Constructing Cyclic Peptides Using an On-Tether Sulfonium Center

Published on: September 28, 2022

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局所生成 β-ターン強制折りたたみによる1ポットサイクリングから大型ペプチドミメティックマクロサイクル

Fei Gou1, Di Shi1, Bohan Kou1

  • 1Department of Chemistry, College of Chemistry and Chemical Engineering, The MOE Key Laboratory of Spectrochemical Analysis and Instrumentation, and Collaborative Innovation Center of Chemistry for Energy Materials (iChEM), Xiamen University, Xiamen 361005, China.

Journal of the American Chemical Society
|April 10, 2023
PubMed
まとめ

研究者は,アミドチオウレア分子を用いて大きなペプチドミメティックマクロサイクルのための新しいワンポット合成を開発した. これらのマクロサイクルはアニオン結合時に構造変化を示し,水から硫酸アニオンを取り除くことができます.

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