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Updated: Aug 3, 2025

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P450単酸化酵素へのC-C結合分裂活動

Justin C Miller1, Joel H Z Lee2, Mark A Mclean3

  • 1Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.

Journal of the American Chemical Society
|April 12, 2023
PubMed
まとめ

研究者は,α-ヒドロキシケトンの炭素-炭素結合を裂くために微生物のサイトクロームP450 (CYP) 酵素を設計しました. この合成されたCYP酵素はライアース活性を示し,CYPの触媒機構と中間物質に関する新しい洞察を提供している.

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