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内生レトロウイルスに対する抗体は,肺がんの免疫療法を促進する

Kevin W Ng1, Jesse Boumelha2, Katey S S Enfield3

  • 1Retroviral Immunology Laboratory, The Francis Crick Institute, London, UK.

Nature
|April 12, 2023
PubMed
まとめ

肺がんにおける三次リンパ性構造 (TLS) は,免疫療法に対するよりよい反応と相関しています. 免疫療法によって増強された内生レトロウイルス (ERV) 抗体は,抗腫瘍活性を促進し,有効性のためにTLSを必要とします.

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