関連する実験動画

Updated: Aug 2, 2025

An Oncogenic Hepatocyte-Induced Orthotopic Mouse Model of Hepatocellular Cancer Arising in the Setting of Hepatic Inflammation and Fibrosis
06:38

An Oncogenic Hepatocyte-Induced Orthotopic Mouse Model of Hepatocellular Cancer Arising in the Setting of Hepatic Inflammation and Fibrosis

Published on: September 12, 2019

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免疫チェックポイント療法 - 現在の見通しと将来の方向

Padmanee Sharma1, Sangeeta Goswami2, Deblina Raychaudhuri3

  • 1Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; The Immunotherapy Platform, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; James P. Allison Institute, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Cell
|April 14, 2023
PubMed
まとめ

免疫チェックポイント療法 (ICT) は長期にわたる癌の治療効果をもたらしますが,反応率は変動します. 免疫的および非免疫的要因を理解することは,患者の選択を最適化し,ICTの有効性を改善するために不可欠です.

キーワード:
CTLA-4 について情報通信技術PD-1 についてPD-L1 について組み合わせバイオマーカー細胞毒性Tリンパ球関連タンパク質4免疫チェックポイント療法免疫関連の有害事象イラースプログラム細胞死タンパク質 1プログラム死亡リガンド 1リバース翻訳

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