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Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model
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皮膚がんのスクリーニング:米国の予防サービスタスクフォースの勧告声明

, Carol M Mangione1, Michael J Barry2

  • 1University of California, Los Angeles.

JAMA
|April 18, 2023
PubMed
まとめ

米国予防サービスタスクフォースは,無症状の個人に皮膚がんのスクリーニングを推奨する十分な証拠が見つかりませんでした. 視覚的な皮膚検査の利点と害を特定するには,さらなる研究が必要です.

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科学分野:

  • 皮膚科
  • 予防医学
  • 腫瘍学

背景:

  • 皮膚がんはアメリカで最も一般的な癌で メラノーマは最も多くの死者を 引き起こしています
  • メラノーマは白人に多く見られるが 肌の色が濃い人は 後で診断される
  • 早期発見と治療は より良い結果を得るために不可欠です

研究 の 目的:

  • 皮膚がんのスクリーニングに関する2016年の勧告を更新する.
  • 症状のない個人をスクリーニングする際の利害を体系的に検討する.
  • 皮膚がんの検出に関する臨床ガイドラインを参考にする.

主な方法:

  • 米国予防サービスタスクフォース (USPSTF) が委託した体系的なレビュー.
  • 皮膚病変歴のない無症状の青少年および成人の皮膚癌のスクリーニングに焦点を当てた.
  • 臨床医による視覚的な皮膚検査の利点と害に関する証拠の評価

主要な成果:

  • USPSTFは,スクリーニングの利益と害に関する証拠が不十分であることが判明しました.
  • 現状の証拠は,無症状の個人の定期的なスクリーニングを支持したり反論したりしません.
  • 皮膚がんスクリーニングの有効性を確立するには,さらなる研究が必要です.

結論:

  • USPSTFは,皮膚がんのスクリーニングのための視覚皮膚検査の利益と害のバランスを評価するのに十分な証拠がないと結論付けています.
  • "I"の文は 証拠が不十分であることを表しています
  • 無症状の集団における皮膚がんスクリーニングの推奨値は未定です.