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Updated: Aug 2, 2025

Synthesis of Wavelength-shifting DNA Hybridization Probes by Using Photostable Cyanine Dyes
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Synthesis of Wavelength-shifting DNA Hybridization Probes by Using Photostable Cyanine Dyes

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アルケン-アルキン [2 + 2] フォトサイクロアディションによるプログラム可能なDNAインターストランドクロスリンク

Hermann Neitz1, Irene Bessi1, Jochen Kuper2

  • 1Institute of Organic Chemistry, Universität Würzburg, Am Hubland, 97074 Würzburg, Germany.

Journal of the American Chemical Society
|April 18, 2023
PubMed
まとめ

研究者は光誘発DNAクロスリンク方法を開発し, 修正された核酸を使用した. この技術は効率的に共性クロスリンクを作成し,DNAの解き放たれを防止し,生化学および構造生物学の応用の可能性を示しています.

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