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Updated: Aug 2, 2025

A Two-Step Protocol for Umpolung Functionalization of Ketones Via Enolonium Species
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A Two-Step Protocol for Umpolung Functionalization of Ketones Via Enolonium Species

Published on: August 16, 2018

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ノーマル対クロスにおける運動,熱力学,動的制御 [2 + 2] エネ-ケテニミニウムイオンのサイクル添加: 計算による理解,予測,実験的検証

Pan Zhang1, Zhi-Xiang Yu1

  • 1Beijing National Laboratory for Molecular Sciences (BNLMS), Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry, Peking University, Beijing 100871, China.

Journal of the American Chemical Society
|April 19, 2023
PubMed
まとめ

この研究は,クロス [2 + 2] 反応が難しい理由を説明し,ビサイクロ [3.1.1] ヘプタン骨格の達成方法を示しています. 新しい方法により これらの重要な製薬構成要素を合成できます

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