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Updated: Aug 2, 2025

Oligopeptide Competition Assay for Phosphorylation Site Determination
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Published on: May 18, 2017

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FNIP1のAMPKリン酸化によるリソソームとミトコンドリアの生体生成の誘導

Nazma Malik1, Bibiana I Ferreira1, Pablo E Hollstein1

  • 1Molecular and Cell Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA, USA.

Science (New York, N.Y.)
|April 20, 2023
PubMed
まとめ

ミトコンドリア損傷はアデノシンモノフォスファート活性化タンパク質キナーゼ (AMPK) を活性化させ,フォリキュリン相互作用タンパク質1 (FNIP1) をリン酸化する. これはTFEB核転移を誘発し,リゾソームとミトコンドリアの生体生成を開始します.

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