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Updated: Aug 2, 2025

Facile Preparation of 2Z,4E-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
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Facile Preparation of 2Z,4E-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate

Published on: June 21, 2017

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ストレスを駆動するサイクルアレン反応の明確なモード:中央アレン炭素原子へのグループ移行

Qian Xu1, Thomas R Hoye1

  • 1Department of Chemistry, University of Minnesota, 207 Pleasant St. SE, Minneapolis, Minnesota 55455, United States.

Journal of the American Chemical Society
|April 22, 2023
PubMed
まとめ

周期性アレンは,新しいグループ移行戦略を使用して,代用フェノールに変換できます. この方法は伝統的な反応の限界を克服し,複雑な分子合成を可能にします.

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The Cope rearrangement is classified as a [3,3] sigmatropic shift in 1,5-dienes, leading to a more stable, isomeric 1,5-diene. The reaction involves a concerted movement of six electrons, four from two π bonds and two from a σ bond, via an energetically favorable chair-like transition state.
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The Claisen rearrangement is a [3,3] sigmatropic rearrangement of allyl vinyl ethers to unsaturated carbonyl compounds. The rearrangement is a concerted pericyclic reaction proceeding via a chair-like transition state.
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For example, in...
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