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Updated: Aug 1, 2025

Single-Molecule Imaging of Lateral Mobility and Ion Channel Activity in Lipid Bilayers using Total Internal Reflection Fluorescence TIRF Microscopy
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Single-Molecule Imaging of Lateral Mobility and Ion Channel Activity in Lipid Bilayers using Total Internal Reflection Fluorescence TIRF Microscopy

Published on: February 17, 2023

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バクテリアトランスポーター EmrE のマイクロ秒運動

Alexander A Shcherbakov1, Merissa Brousseau2, Katherine A Henzler-Wildman2

  • 1Department of Chemistry, Massachusetts Institute of Technology, 170 Albany Street, Cambridge, Massachusetts 02139, United States.

Journal of the American Chemical Society
|April 25, 2023
PubMed
まとめ

バクテリアトランスポーター EmrEは,基板の結合と放出を容易にするためにマイクロ秒の骨幹運動を使用します. これらのダイナミクスは,テトラ ((4-フッロフェニル) フォスフォニウムに結合した変異体で観察され,多剤耐性トランスポーターメカニズムの洞察を提供します.

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