Jove
Visualize
お問い合わせ
JoVE
x logofacebook logolinkedin logoyoutube logo
JoVEについて
概要リーダーシップブログJoVEヘルプセンター
著者向け
出版プロセス編集委員会範囲と方針査読よくある質問投稿
図書館員向け
推薦の声購読アクセスリソース図書館諮問委員会よくある質問
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experimentsアーカイブ
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教員リソースセンター教員サイト
利用規約
プライバシーポリシー
ポリシー

関連する概念動画

Conformations of Cyclohexane02:11

Conformations of Cyclohexane

12.7K
Cyclohexane does not exist in a planar form due to the high angle and torsional strain it would experience in the planar structure. Instead, it adopts non-planar chair and boat conformations.
The chair form is the most stable and derives its name from its resemblance to the “easy chair.” In the chair conformation, two carbon atoms are arranged out-of-plane — one above and one below, minimizing the torsional strain. In the chair form, the bond angle is very close to the ideal...
12.7K
Stereoisomerism of Cyclic Compounds02:33

Stereoisomerism of Cyclic Compounds

9.0K
In this lesson, we delve into the role of ring conformation and its stability, which determines the spatial arrangement and, consequently, the molecular symmetry and stereoisomerism of cyclic compounds. 1,2-Dimethylcyclohexane is used as a case study to evaluate the possible number of stereoisomers. Here, given the multiple (n = 2) chiral centers, there are 2n = 4 possible configurations that lack a plane of symmetry, as the ring skeleton exists in a non-planar chair conformation. In addition,...
9.0K
Aromatic Hydrocarbon Cations: Structural Overview01:18

Aromatic Hydrocarbon Cations: Structural Overview

2.9K
Cycloheptatriene is a neutral monocyclic unsaturated hydrocarbon that consists of an odd number of carbon atoms and an intervening sp3 carbon in the ring. The three double bonds in the ring correspond to 6 π electrons, which is a Huckel number, and therefore satisfies the criteria of 4n + 2 π electrons. However, the intervening sp3 carbon disrupts the continuous overlap of p orbitals. As a result, cycloheptatriene is not aromatic.
Removing one hydrogen from the intervening CH2 group...
2.9K
Chair Conformation of Cyclohexane02:02

Chair Conformation of Cyclohexane

14.8K
The chair conformation is the most stable form of cyclohexane due to the absence of angle and torsional strain. The absence of angle strain is a result of cyclohexane’s bond angle being very close to the ideal tetrahedral bond angle of 109.5° in its chair conformer. Similarly, the torsional strain is also absent owing to the perfectly staggered arrangement of bonds.
The hydrogen atoms linked to carbons are arranged in two different axial and equatorial orientations to achieve this...
14.8K
Conformations of Cycloalkanes02:29

Conformations of Cycloalkanes

11.9K
Adolf von Baeyer attempted to explain the instabilities of small and large cycloalkane rings using the concept of angle strain — the strain caused by the deviation of bond angles from the ideal 109.5° tetrahedral value for sp3  hybridized carbons. However, while cyclopropane and cyclobutane are strained, as expected from their highly compressed bond angles, cyclopentane is more strained than predicted, and cyclohexane is virtually strain-free. Hence, Baeyer’s theory that...
11.9K
Stability of Conjugated Dienes01:28

Stability of Conjugated Dienes

3.5K
Introduction
A comparison of the enthalpies of hydrogenation of dienes reveals that conjugated dienes release less heat on hydrogenation, rendering them more stable than their nonconjugated analogs.
3.5K

こちらも読む

関連記事

共著者、ジャーナル、引用グラフによってこの研究に関連する記事。

並び替え
Same author

Semaglutide for Primary Prevention of Major Adverse Cardiac and Cerebrovascular Events in Patients with Type 2 Diabetes and Comorbid Rheumatoid Arthritis: A Target-Trial Emulation.

European heart journal. Cardiovascular pharmacotherapy·2026
Same author

The Cooperative Double Helicenyl Fragment Model: Efficiently Predicting Stereochemical Stability of Triphenylene-Cored Multiple Helicenes.

The journal of physical chemistry. A·2026
Same author

Global trends in lipoprotein(a) and high-sensitivity c-reactive protein testing in patients with established atherosclerotic cardiovascular disease.

American journal of preventive cardiology·2026
Same author

Asymmetric Total Synthesis of C2-OH Lycopodium Alkaloids (-)-Palhinine B, (-)-Palhinine C, and (+)-Palhinine B Enabled by Stereocontrolled Diels-Alder Strategy.

Organic letters·2026
Same author

RRM2 as a biomarker and therapeutic target in letrozole resistant estrogen receptor positive breast cancer.

Scientific reports·2026
Same author

Direct oral anticoagulant monotherapy vs combination therapy with antiplatelets in chronic coronary syndrome patients with prior percutaneous coronary intervention requiring anticoagulation: A meta-analysis.

American heart journal·2026
Same journal

Linker Engineering toward NIR-II Metal-Organic Framework with Maximal Emission beyond 1000 nm for Inflammatory Bowel Disease Imaging.

Journal of the American Chemical Society·2026
Same journal

Observing Kinetic Selectivity in Anthracene Photodimerization through Selective Quenching by Excited States of Proximate Rare Earth Cations.

Journal of the American Chemical Society·2026
Same journal

Sequence-Dependent Folding of Recognition-Encoded Melamine Oligomers.

Journal of the American Chemical Society·2026
Same journal

Large Thermo- and Mechanosalient Actuation via Cooperative Twist Elasticity-Induced Packing Motif Conversion.

Journal of the American Chemical Society·2026
Same journal

Discovery and Biosynthesis of Lanthipeptides Featuring an Azepinoindole Scaffold by Radical <i>S</i>-Adenosylmethionine Enzyme-Catalyzed C-C Bond Formation.

Journal of the American Chemical Society·2026
Same journal

Enantiopurity-Controlled Magnetism in a Two-Dimensional Organic-Inorganic Material.

Journal of the American Chemical Society·2026
関連記事をすべて見る

関連する実験動画

Updated: Aug 1, 2025

Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives
09:22

Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives

Published on: February 7, 2017

7.9K

高度歪んだ多重ヘリケーン:合成,構造分析,および特性

Hsiao-Ci Huang1, Ya-Chu Hsieh1, Pei-Lun Lee1

  • 1Department of Chemistry, National Cheng Kung University, Tainan 70101, Taiwan.

Journal of the American Chemical Society
|April 26, 2023
PubMed
まとめ
この要約は機械生成です。

研究者らは,ユニークな構造を持つ新しいヘクサポールヘリケーン (HHs) とノンプルヘリケーン (NHs) を合成した. この方法により,代替剤を簡単に導入し,骨幹を効率的に拡張し,詳細な構造とエネルギー分析を可能にします.

さらに関連する動画

Preparation of a Corannulene-functionalized Hexahelicene by CopperI-catalyzed Alkyne-azide Cycloaddition of Nonplanar Polyaromatic Units
09:35

Preparation of a Corannulene-functionalized Hexahelicene by CopperI-catalyzed Alkyne-azide Cycloaddition of Nonplanar Polyaromatic Units

Published on: September 18, 2016

11.6K
Construction and Systematical Symmetric Studies of a Series of Supramolecular Clusters with Binary or Ternary Ammonium Triphenylacetates
06:35

Construction and Systematical Symmetric Studies of a Series of Supramolecular Clusters with Binary or Ternary Ammonium Triphenylacetates

Published on: February 15, 2016

8.2K

関連する実験動画

Last Updated: Aug 1, 2025

Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives
09:22

Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives

Published on: February 7, 2017

7.9K
Preparation of a Corannulene-functionalized Hexahelicene by CopperI-catalyzed Alkyne-azide Cycloaddition of Nonplanar Polyaromatic Units
09:35

Preparation of a Corannulene-functionalized Hexahelicene by CopperI-catalyzed Alkyne-azide Cycloaddition of Nonplanar Polyaromatic Units

Published on: September 18, 2016

11.6K
Construction and Systematical Symmetric Studies of a Series of Supramolecular Clusters with Binary or Ternary Ammonium Triphenylacetates
06:35

Construction and Systematical Symmetric Studies of a Series of Supramolecular Clusters with Binary or Ternary Ammonium Triphenylacetates

Published on: February 15, 2016

8.2K

科学分野:

  • 有機化学
  • 超分子化学
  • 材料科学

背景:

  • ヘリケンは独特の螺旋構造を持つキラルな芳香炭化水素である.
  • 複雑なヘリケーン構造のための新しい合成経路の開発は,それらの特性を探求するために不可欠です.

研究 の 目的:

  • 新しいヘクサポルヘリケーン (HHs) とノンプルヘリケーン (NHs) を合成する.
  • 独特の構造特性を調査し,効率的な合成方法論を開発する.
  • ダイアステレオメアを計算して予測する.

主な方法:

  • イオドサイクリングとパラジウム触媒による無効化を含む2段階の合成.
  • 3次元構造の解明のためのX線結晶学.
  • チラルの解像度とエナチオメリゼーションバリアの実験的決定.
  • ディアステロエーマーエネルギー予測のための密度関数理論 (DFT) の計算.

主要な成果:

  • HHsとNHsの合成が成功し,末端ナフタレンユニットを共有しました.
  • 3つのC1対称のHHと1つのC3対称のNHの結晶構造の解明
  • HH (31.2 kcal/mol) のエナチオメリゼーションバリアの実験的決定.
  • ダイアステレオメアの安定性を予測するためのDFTベースの方法の開発.

結論:

  • 複合ヘリケンの容易かつ地域選択的な合成経路が確立された.
  • 合成されたHHsとNHsは独特の構造モチーフを示しています.
  • 計算方法は,ダイアステレオメアの安定性を効率的に予測し,新しいヘリケンのアーキテクチャの設計に役立ちます.