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Updated: Aug 1, 2025

Combining Mitotic Cell Synchronization and High Resolution Confocal Microscopy to Study the Role of Multifunctional Cell Cycle Proteins During Mitosis
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Combining Mitotic Cell Synchronization and High Resolution Confocal Microscopy to Study the Role of Multifunctional Cell Cycle Proteins During Mitosis

Published on: December 5, 2017

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CDC20のトランスレーション性アイソフォームは,ミトス停止期間を調整する

Mary-Jane Tsang1,2, Iain M Cheeseman3,4

  • 1Whitehead Institute for Biomedical Research, Cambridge, MA, USA.

Nature
|April 26, 2023
PubMed
まとめ

細胞は,CDC20タンパク質同型を用いてミトスの停止と滑り方をバランスします. 切断されたCDC20同型はチェックポイントの制御をバイパスし,細胞周期の終了を促進し,がん治療の感受性に影響を与えます.

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