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Updated: Jul 31, 2025

A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones
07:30

A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones

Published on: January 21, 2020

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SmI2-メディエートされたケトンとの分子間還元結合によるインドールのエナチオセレクティブ脱オマティゼーション

Wen-Yun Zhang1, Hu-Chong Wang1, Ye Wang1

  • 1State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 345 Lingling Lu, Shanghai 200032, China.

Journal of the American Chemical Society
|May 1, 2023
PubMed
まとめ

この研究は,サムリウム二酸化物 (SmI2) とキラルリガンドを使用してインドリンを合成するためのエナンチオセレクティブ方法を導入する. この新しいアプローチは,還元結合による炭素-炭素結合の形成において高い収量とステレオ選択性を達成します.

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