関連する実験動画

Updated: Jul 30, 2025

Detection of Retrotransposition Activity of Hot LINE-1s by Long-Distance Inverse PCR
10:54

Detection of Retrotransposition Activity of Hot LINE-1s by Long-Distance Inverse PCR

Published on: July 27, 2019

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正常な結腸内皮質における広範な体内L1逆転移

Chang Hyun Nam1, Jeonghwan Youk1,2,3, Jeong Yeon Kim2

  • 1Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea.

Nature
|May 10, 2023
PubMed
まとめ

ソマティック細胞は,移動性要素である長い間隔の核元素-1 (L1) の逆転移によってゲノム変異を蓄積する. この研究は,L1の活性が正常な細胞で,年齢とともに増加し,大腸がんでも増加していることを明らかにしています.

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Analysis of LINE-1 Retrotransposition at the Single Nucleus Level11:52

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