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Updated: Jul 30, 2025

Toeprinting Analysis of Translation Initiation Complex Formation on Mammalian mRNAs
10:37

Toeprinting Analysis of Translation Initiation Complex Formation on Mammalian mRNAs

Published on: May 10, 2018

12.6K

トランスクリプション開始部位 mRNAイソフォーム選択

Carlos Alfonso-Gonzalez1, Ivano Legnini2, Sarah Holec3

  • 1Max-Planck-Institute of Immunobiology and Epigenetics, 79108 Freiburg, Germany; Faculty of Biology, Albert Ludwig University, 79104 Freiburg, Germany; International Max Planck Research School for Molecular and Cellular Biology (IMPRS-MCB), 79108 Freiburg, Germany.

Cell
|May 13, 2023
PubMed
まとめ

転写開始部位の選択は,メッセンジャーRNA (mRNA) のアイソフォームの多様性と組織アイデンティティに重大な影響を及ぼします. 特定のプロモーターはスプライシングとポリアデニレーションを調節し,遺伝子発現と細胞特有の機能に影響を与えます.

キーワード:
5'−3' カップリングドロソフィラ代替ポリアデニレーション人間の脳オーガノイドロングリードシーケンシングmRNA アイソフォーム神経系p300/CBP についてトランスクリプション転写開始場所

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