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Updated: Jul 28, 2025

A Two-Step Protocol for Umpolung Functionalization of Ketones Via Enolonium Species
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A Two-Step Protocol for Umpolung Functionalization of Ketones Via Enolonium Species

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α,β-不飽和エステルおよびアミドに対する触媒エナチオセレクティブ内分子オキサミハエル反応

Guanglong Su1, Michele Formica1, Ken Yamazaki1,2

  • 1Department of Chemistry, Chemistry Research Laboratory, University of Oxford, 12 Mansfield Road, OX1 3TA Oxford, U.K.

Journal of the American Chemical Society
|May 30, 2023
PubMed
まとめ

新しい二機能イミノフォスフォラン (BIMP) 触媒は,高効率のエナチオセレクティブの分子内オクサミハエル反応を可能にします. この方法は,生物学的活性分子と天然製品の価値あるエナチオ濃縮の構成要素にアクセスできます.

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