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Updated: Jul 28, 2025

In Vitro Selection of Engineered Transcriptional Repressors for Targeted Epigenetic Silencing
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エンジニアリングされたtRNAは,細胞と体内の無意味な変異を抑制する

Suki Albers1, Elizabeth C Allen2, Nikhil Bharti1

  • 1Institute of Biochemistry and Molecular Biology, University of Hamburg, Hamburg, Germany.

Nature
|May 31, 2023
PubMed
まとめ

研究者達は遺伝子病の原因である 無意味な変異を抑制するために 設計されたトランスファーRNA (tRNA) を開発した. この新しい治療法により マウスとヒトの細胞で 機能するタンパク質の生成が回復し 新しい治療戦略が期待されます

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