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Updated: Jul 28, 2025

Heterogeneity Mapping of Protein Expression in Tumors using Quantitative Immunofluorescence
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トランスクリプション内腫瘍の異質性の特徴は,数千の腫瘍にわたって見られる

Avishai Gavish1, Michael Tyler1, Alissa C Greenwald1

  • 1Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.

Nature
|May 31, 2023
PubMed
まとめ

この研究では,24種類の腫瘍から1,163の単細胞RNAシーケンシングデータを統合して,転写内腫瘍異質性 (ITH) をマッピングした. 41のコンセンサス遺伝子メタプログラムが特定され,腫瘍形成前のITHパターンが明らかになりました.

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