関連する実験動画

Updated: May 1, 2026

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing
11:22

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing

Published on: October 15, 2019

28.4K

高複合生物活性スクリーニングは,ヒトと微生物の代謝体とGPCRomeの相互作用を明らかにする

Haiwei Chen1, Connor E Rosen2, Jaime A González-Hernández2

  • 1Institute of Pediatrics, Children's Hospital of Fudan University, and Shanghai Key Laboratory of Medical Epigenetics, International Co-laboratory of Medical Epigenetics and Metabolism (Ministry of Science and Technology), Institutes of Biomedical Sciences, Shanghai Medical College, Fudan University, Shanghai 200032, China; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.

Cell
|June 15, 2023
PubMed
まとめ

科学者たちは,メタボリート-Gタンパク質結合受容体 (GPCR) の相互作用を研究するための新しいスクリーニング技術であるPRESTO-Salsaを開発しました. この方法は,ヒトの代謝産物と微生物から多数の新しいGPCRアゴニストを特定しました.

キーワード:
Gタンパク質結合受容体 (GPCR)高通量スクリーニング人間のメタボローム微生物群微生物群の代謝物質

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