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Updated: Jul 26, 2025

Genetic Manipulation of Cerebellar Granule Neurons In Vitro and In Vivo to Study Neuronal Morphology and Migration
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Genetic Manipulation of Cerebellar Granule Neurons In Vitro and In Vivo to Study Neuronal Morphology and Migration

Published on: March 17, 2014

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WAPLは,神経配線を制御するプロトカデリン同型多様性のレオスタットとして機能する

Lea Kiefer1,2, Anna Chiosso1,2, Jennifer Langen1,2,3

  • 1Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA 94158, USA.

Science (New York, N.Y.)
|June 22, 2023
PubMed
まとめ

脳の配線に不可欠な,細胞型特異のクラスター化されたプロトカデリン (Pcdh) 発現は,コヘシンとWAPLに依存する. これらのタンパク質は Pcdh アイソフォームの多様性を調節し,神経の発達における異なる軸索パターンを可能にします.

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Dissection of Xenopus laevis Neural Crest for in vitro Explant Culture or in vivo Transplantation09:07

Dissection of Xenopus laevis Neural Crest for in vitro Explant Culture or in vivo Transplantation

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Modeling Paracrine Noncanonical Wnt Signaling In Vitro11:14

Modeling Paracrine Noncanonical Wnt Signaling In Vitro

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