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Updated: Jul 25, 2025

Methods to Classify Cytoplasmic Foci as Mammalian Stress Granules
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QKIは内部m7G変異したトランスクリプトをストレス粒に変換し,mRNA代謝を調節する

Zhicong Zhao1, Ying Qing2, Lei Dong2

  • 1Department of Systems Biology, Beckman Research Institute of City of Hope, Monrovia, CA 91016, USA; Department of Liver Surgery, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China.

Cell
|June 28, 2023
PubMed
まとめ

振動タンパク質 (QKI) は,内部のN7-メチルグアノシン (m7G) 改変をメッセンジャーRNA (mRNA) に結合させる. この相互作用はmRNAの安定性と翻訳を調節し,がん細胞の化学療法に対する感受性に影響を及ぼします.

キーワード:
G3BP1 についてMETTL1 についてN(7) メチルグアノシンQKI について薬剤耐性m ((7) G についてmRNAの代謝mRNAの安定性についてストレス・グラニュル翻訳規制

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