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Updated: Jul 25, 2025

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代替ビタミンEメタボリットの結合部位をターゲットにすることで,非正規のPPARγ調節が可能になる

Silvia Arifi1, Julian A Marschner2, Julius Pollinger1

  • 1Institute of Pharmaceutical Chemistry, Goethe University Frankfurt, D-60438 Frankfurt, Germany.

Journal of the American Chemical Society
|June 29, 2023
PubMed
まとめ

研究者らは,第二の結合部位をターゲットにすることで,転写因子PPARγ (ペロキシゾーム増殖因子活性化受容体ガンマ) を調節する新しい方法を発見した. この発見は,従来のPPARγ活性化を超えた新しい治療戦略を示唆しています.

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