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Updated: Jul 24, 2025

Solid-phase Synthesis of [4.4] Spirocyclic Oximes
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Solid-phase Synthesis of [4.4] Spirocyclic Oximes

Published on: February 6, 2019

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同結晶化および固体メカノケミカルプロセスによるピラー[5]アレンの二重選択性ロタキサン合成

Keisuke Wada1, Kiichi Yasuzawa1, Shixin Fa1,2

  • 1Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Nishikyo-ku, Kyoto 615-8510, Japan.

Journal of the American Chemical Society
|July 6, 2023
PubMed
まとめ

ダイアステロエーマー間のエネルギー差が小さいため,キラルロタキサンを合成することは困難です. この研究では,ロタキサン合成における高ダイアステロ選択性を達成するために,共結晶化を用いた固相法が導入されています.

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