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Updated: Jul 23, 2025

Protein WISDOM: A Workbench for In silico De novo Design of BioMolecules
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タンパク質の構造と機能をRFdiffusionで新たに設計する

Joseph L Watson1,2, David Juergens1,2,3, Nathaniel R Bennett1,2,3

  • 1Department of Biochemistry, University of Washington, Seattle, WA, USA.

Nature
|July 11, 2023
PubMed
まとめ

新しい深層学習の枠組みであるRoseTTAFold拡散 (RFdiffusion) は,多様な機能タンパク質の設計を可能にします. この方法は,タンパク質結合剤,対称なアセンブリ,および様々な用途のための支架を作成する上で優れています.

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