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Updated: Jul 23, 2025

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

Published on: February 7, 2019

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ペプチドマクロサイクルのためのフッ化スピロヘロサイクルのカスケード合成

Angel Mendoza1, Salvador J Bernardino1, Morris J Dweck1

  • 1Department of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, California 90095, United States.

Journal of the American Chemical Society
|July 13, 2023
PubMed
まとめ

オクタフローロcyclopentene (OFCP) は,ペプチドから複雑なフッ素ポリサイクルの効率的な合成を可能にする. この触媒のない方法は 新種の分子ハイブリッドを生み出し 薬の発見の可能性を秘めています

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