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Updated: Jul 23, 2025

Three-Dimensional Bone Extracellular Matrix Model for Osteosarcoma
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デノスマブで治療された巨細胞腫瘍の子供の転移性硬化症

Vivian Szymczuk1, Alison Boyce1, Nadia Merchant2

  • 1Metabolic Bone Disorders Unit, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD, USA.

Lancet (London, England)
|July 15, 2023
PubMed
まとめ

No abstract available in PubMed .

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関連する概念動画

Bone Disorders01:29

Bone Disorders

Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
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