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Updated: Jul 23, 2025

Investigating the Pathogenesis of MYH7 Mutation Gly823Glu in Familial Hypertrophic Cardiomyopathy using a Mouse Model
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Investigating the Pathogenesis of MYH7 Mutation Gly823Glu in Familial Hypertrophic Cardiomyopathy using a Mouse Model

Published on: August 8, 2022

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サルコメア変異の微細構造および微細血管現象 媒介者および露骨な高縮性心筋病

George Joy1,2, Christopher I Kelly3, Matthew Webber2,4,5

  • 1Barts Heart Centre, Barts Health NHS Trust, London, UK (G.J., I.P., P.V., R.K.H., H.K., A.B., M.L., K.S., S.A.M., M.O., C.M., R.H.D., P.D.L., J.C.M., L.R.L.).

Circulation
|July 18, 2023
PubMed
まとめ

筋細胞の乱れとマイクロ血管疾患 (MVD) は,高縮性心筋病 (HCM) の初期指標である. これらの変化は,過剰増殖なしでも検出され,病気を修正する治療法の重要なバイオマーカーとして機能します.

キーワード:
心筋病 縮症拡散テンソルイメージング磁気共鳴画像検査マイクロ循環パルフュージョンサルコメア

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