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Updated: Jul 23, 2025

Determination of Protein-ligand Interactions Using Differential Scanning Fluorimetry
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Determination of Protein-ligand Interactions Using Differential Scanning Fluorimetry

Published on: September 13, 2014

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熱力学モデルと実験データは,排除された体積メカニズムに従って糖質がタンパク質を安定させることを明らかにする

Andrea Arsiccio1, Tim Sarter2, Ilaria Polidori2

  • 1Department of Chemistry and Biochemistry, University of California, Santa Barbara, California 93106, United States.

Journal of the American Chemical Society
|July 19, 2023
PubMed
まとめ

この研究は,コソルトがタンパク質の安定性にどのように影響するかを理解するための熱力学モデルを導入します. シミュレーションと実験によって検証されたように,糖は主に排斥された体積メカニズムを通じてタンパク質を安定させます.

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