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Updated: Jul 22, 2025

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Mn/FeコファクターによるアリファティックC-H結合の酵素性水酸化

Magan M Powell1, Guodong Rao2, R David Britt2

  • 1Department of Chemistry, University of California, Berkeley, Berkeley, California 94720, United States.

Journal of the American Chemical Society
|July 20, 2023
PubMed
まとめ

この研究は,以前はC-H結合の活性化について知られていなかったマンガンが,強いアリファティックC-H結合を機能化するために,酵素AibH1H2にとって不可欠であることを明らかにしています. この発見は,生物学的酸化反応におけるマンガン-鉄共因子の既知の役割を拡大する.

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