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Updated: Jul 22, 2025

A Microwave-Assisted Direct Heteroarylation of Ketones Using Transition Metal Catalysis
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活性化されていないC−H結合にナイトレン挿入による人工メタロ酵素触媒によるエナチオセレクティブアミデーション

Kun Yu1, Zhi Zou1, Nico V Igareta1

  • 1Department of Chemistry, University of Basel, Mattenstrasse 24a, BPR 1096, Basel CH-4058, Switzerland.

Journal of the American Chemical Society
|July 20, 2023
PubMed
まとめ

人工金属酵素 (ArM) は,活性化されていないC ((sp3) -H結合のエナチオセレクティブC-Hアミデーションを可能にします. この突破は高い活性と選択性を達成し,新しい窒素含有分子合成の道を開きました.

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