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Updated: Jul 22, 2025

Stimulation of Cytoplasmic DNA Sensing Pathways In Vitro and In Vivo
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Published on: September 18, 2014

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動物におけるcGAS-STINGによる先天的な免疫感知は,予期せぬ伝達者を明らかにする

Leonie Unterholzner1

  • 1Division of Biomedical and Life Sciences, Faculty of Health and Medicine, Lancaster University, Lancaster LA1 4YQ, UK.

Cell
|July 21, 2023
PubMed
まとめ

研究者らは数千のcGASのような受容体を発見し,動物間で保存された先天的な免疫経路を明らかにしました. この発見は,サイクルGMP-AMP合成酵素 (cGAS) とSTING関連血管病 (STING) が様々な種における病原体を検出する方法を明らかにしています.

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