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Updated: Jul 21, 2026

Models and Methods to Evaluate Transport of Drug Delivery Systems Across Cellular Barriers
18:57

Models and Methods to Evaluate Transport of Drug Delivery Systems Across Cellular Barriers

Published on: October 18, 2013

緊密な結合は,脂質分子が1つの上皮細胞から次の上皮細胞に拡散することを許さない

G van Meer, B Gumbiner, K Simons

    Nature
    |August 14, 1986
    PubMed
    まとめ

    緊密な結節 (ゾヌラ・オクラデンス) は上皮細胞を封じ込めますが,脂質シリンダーモデルとは異なり,細胞間の脂質通過を許しません. この発見は,緊密な交差点の構造と機能に関する既存のモデルに挑戦しています.

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