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Updated: Jul 20, 2025

Novel Atomic Force Microscopy Based Biopanning for Isolation of Morphology Specific Reagents against TDP-43 Variants in Amyotrophic Lateral Sclerosis
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Novel Atomic Force Microscopy Based Biopanning for Isolation of Morphology Specific Reagents against TDP-43 Variants in Amyotrophic Lateral Sclerosis

Published on: February 12, 2015

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TDP-43は,タイプAのFTLD-TDPで明確な折りたたみを持つアミロイドフィラメントを形成する

Diana Arseni1, Renren Chen1, Alexey G Murzin1

  • 1MRC Laboratory of Molecular Biology, Cambridge, UK.

Nature
|August 2, 2023
PubMed
まとめ

異常なTAR DNA結合タンパク質43 (TDP-43) 組成はALSやFTLDのような神経変性疾患を引き起こす. 研究者らは,ALSとタイプBのFTLD-TDPとは異なる,新しいTDP-43フィラメント構造を発見した.

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Analysis of β-Amyloid-induced Abnormalities on Fibrin Clot Structure by Spectroscopy and Scanning Electron Microscopy06:27

Analysis of β-Amyloid-induced Abnormalities on Fibrin Clot Structure by Spectroscopy and Scanning Electron Microscopy

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Purification and Aggregation of the Amyloid Precursor Protein Intracellular Domain10:08

Purification and Aggregation of the Amyloid Precursor Protein Intracellular Domain

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