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Updated: Jul 19, 2025

Reliably Engineering and Controlling Stable Optogenetic Gene Circuits in Mammalian Cells
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Reliably Engineering and Controlling Stable Optogenetic Gene Circuits in Mammalian Cells

Published on: July 6, 2021

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協同組合は規制の特異性と長期の遺伝回路の安定性をもたらします

Meghan D J Bragdon1, Nikit Patel2, James Chuang3

  • 1Biological Design Center, Boston University, Boston, MA 02215, USA; Program in Molecular Biology, Cell Biology and Biochemistry, Boston University, Boston, MA 02215, USA.

Cell
|August 8, 2023
PubMed
まとめ

合成生物学では,協同型転写因子アセンブリを用いて高い遺伝子回路特異性と安定性を達成する. この自然にインスパイアされたアプローチは 宿主のゲノム干渉に対する 頑丈さを高めます

キーワード:
協同活動フィットネス遺伝子回路遺伝子調節モデリング特殊性について合成生物学転写因子イースト亜鉛の指

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