関連する実験動画

Updated: Jul 19, 2025

Single-molecule Manipulation of G-quadruplexes by Magnetic Tweezers
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Single-molecule Manipulation of G-quadruplexes by Magnetic Tweezers

Published on: September 19, 2017

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G4-mRNA ディスプレイ-セクによって選択されたペプチドは,RNA G-クアドルプレックス認識と遺伝子調節を可能にします

Xi Mou1, Chun Kit Kwok1,2

  • 1Department of Chemistry and State Key Laboratory of Marine Pollution, City University of Hong Kong, Kowloon Tong, Hong Kong SAR 999077, China.

Journal of the American Chemical Society
|August 15, 2023
PubMed
まとめ

研究者はG-四重複素 (G4s) を標的とするペプチドを見つけるためにG4-mRNAディスプレイ-Seqを開発した. ヒトのテロメラーゼRNA G4sに特異的に結合し 遺伝子発現を調節するペプチドであるペプチド11を発見しました

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Aptamer-Based Target Detection Facilitated by a 3-Stage G-Quadruplex Isothermal Exponential Amplification Reaction03:38

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