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Updated: Jul 19, 2025

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単細胞ゲノミクスのアーカイブは,DCISの進行中に持続するサブクローンを明らかにしています

Kaile Wang1, Tapsi Kumar2, Junke Wang3

  • 1Department of Systems Biology, UT MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Genetics, UT MD Anderson Cancer Center, Houston, TX 77030, USA.

Cell
|August 16, 2023
PubMed
まとめ

新しい単細胞DNAシーケンシング方法であるArc-wellは,ホルミリン固定型パラフィン埋め込み (FFPE) 腫瘍サンプルを分析します. この方法では,管内がん in situ (DCIS) はしばしばゲノム変化があり,再発性がんとの系統を共有していることが明らかになります.

キーワード:
アーク・ウェルFFPE素材アーカイブサンプル乳がんドクターカルシノマ in situ 再発早期融資について単細胞DNAシーケンシング腫瘍の進化

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