関連する実験動画

Updated: Jul 19, 2025

Assessment of Global DNA Double-Strand End Resection using BrdU-DNA Labeling coupled with Cell Cycle Discrimination Imaging
06:44

Assessment of Global DNA Double-Strand End Resection using BrdU-DNA Labeling coupled with Cell Cycle Discrimination Imaging

Published on: April 28, 2021

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BRCA1およびBRCA2欠乏がんにおけるバックアップDNA修復の長分子傷

Jeremy Setton1, Kevin Hadi2,3,4, Zi-Ning Choo2,3,4

  • 1Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Nature
|August 16, 2023
PubMed
まとめ

癌における同質再結合 (HR) 欠乏症には,相互のペアと呼ばれるユニークなDNAの再編成が含まれています. これらの発見は,特定の修復メカニズムを明らかにし,BRCA1またはBRCA2欠乏性ゲノムの分類を改善します.

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