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Updated: Jul 19, 2025

Preclinical Model of Prenatal Delta-9-Tetrahydrocannabinol Exposure to Assess Its Impact on Neurodevelopmental Outcomes
05:13

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Published on: February 28, 2025

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カナビス使用と妊産婦健康に関する研究

Jamie O Lo1,2, Jason C Hedges1,2, Torri D Metz3

  • 1Department of Obstetrics and Gynecology, Oregon Health & Science University, Portland.

JAMA
|August 17, 2023
PubMed
まとめ

No abstract available in PubMed .

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Tetrahydrocannabinol (THC) is a phytocannabinoid that primarily interacts with the CB1 receptor, a type of G protein-coupled receptor (GPCR) predominantly in and around the chemoreceptor trigger zone (CTZ) and emetic center. THC also blocks the serotonin receptor activity in the dorsal vagal complex (DVC) by inhibiting serotonin release. THC exerts its anti-emetic effects through these interactions, which are beneficial for patients undergoing chemotherapy.
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