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Updated: Jul 18, 2025

Visualization of SARS-CoV-2 using Immuno RNA-Fluorescence In Situ Hybridization
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Published on: December 23, 2020

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生まれながらの免疫細胞およびその祖先におけるコロナウイルス感染症の表遺伝子記憶

Jin-Gyu Cheong1, Arjun Ravishankar2, Siddhartha Sharma3

  • 1Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10065, USA; Immunology and Microbial Pathogenesis Program, Weill Cornell Medicine, New York, NY 10065, USA.

Cell
|August 19, 2023
PubMed
まとめ

重度のCOVID-19は,血液生成幹細胞と前身細胞 (HSPC) を再プログラムし,長続きする先天性免疫記憶を作り出すことができます. HSPCおよびその子孫におけるこれらの表遺伝的変化は,生存者の長期的な免疫機能障害を説明する可能性があります.

キーワード:
コロナウイルスIL-6 についてPASC についてエピジェネティック・メモリーエピゲノム造血幹細胞と祖先細胞モノサイト周辺血液単核細胞のインプット濃縮急性後遺症のSARS-CoV-2感染シングルセル訓練された免疫トランスクリプトーム

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