フォスフォアンチゲンはブチロフィリン3A1と2A1を接着してVγ9Vδ2T細胞を活性化させる

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Updated: Jul 17, 2025

Expansion of Human Peripheral Blood γδ T Cells using Zoledronate
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Expansion of Human Peripheral Blood γδ T Cells using Zoledronate

Published on: September 9, 2011

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Linjie Yuan1, Xianqiang Ma1, Yunyun Yang1,2

  • 1Tsinghua-Peking Center for Life Sciences, State Key Laboratory of Membrane Biology, School of Pharmaceutical Sciences, Tsinghua University, Beijing, China.

Nature
|September 6, 2023
PubMed
まとめ

フォスフォアンチゲンは分子接着剤として作用し,ブチロフィリンBTN3A1とBTN2A1を結合させ,Vγ9Vδ2T細胞を活性化させます. このメカニズムは 癌や感染症の治療に 新たな戦略を提示します

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