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Updated: Jul 16, 2025

Activation and Measurement of NLRP3 Inflammasome Activity Using IL-1β in Human Monocyte-derived Dendritic Cells
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Published on: May 22, 2014

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NLRP1炎症体のチオレドキシン媒介抑制の構造的基礎

Zhikuan Zhang1, Takuma Shibata2, Akiko Fujimura1

  • 1Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan.

Nature
|September 13, 2023
PubMed
まとめ

チオレドキシン (TRX) は,炎症の重要な調節体であるNLRP1炎症体と結合し,それを抑制する. この発見により TRXは生まれつきの免疫の チェックポイントとなり 新しい治療目標となるのです

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