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Updated: Jul 16, 2025

A Scalable, Cell-Based Method for the Functional Assessment of Ube3a Variants
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A Scalable, Cell-Based Method for the Functional Assessment of Ube3a Variants

Published on: October 10, 2022

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前シナプスUbe3a E3リガゼは,BMPシグナリングのダウンレギュレーションによってシナプス除去を促進する

Kotaro Furusawa1, Kenichi Ishii1, Masato Tsuji1

  • 1Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.

Science (New York, N.Y.)
|September 14, 2023
PubMed
まとめ

発達中のシナプス除去には,プレシナプスUbe3aの活性が不可欠である. Ube3a に影響する変異

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