Jove
Visualize
お問い合わせ
JoVE
x logofacebook logolinkedin logoyoutube logo
JoVEについて
概要リーダーシップブログJoVEヘルプセンター
著者向け
出版プロセス編集委員会範囲と方針査読よくある質問投稿
図書館員向け
推薦の声購読アクセスリソース図書館諮問委員会よくある質問
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experimentsアーカイブ
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教員リソースセンター教員サイト
利用規約
プライバシーポリシー
ポリシー

関連する概念動画

Van der Waals Interactions01:24

Van der Waals Interactions

Atoms and molecules interact with each other through intermolecular forces. These electrostatic forces arise from attractive or repulsive interactions between particles with permanent, partial, or temporary charges. The intermolecular forces between neutral atoms and molecules are ion–dipole, dipole–dipole, and dispersion forces, collectively known as van der Waals forces.
Frictional Force01:07

Frictional Force

When a body is in motion, it encounters resistance because the body interacts with its surroundings. This resistance is known as friction, a common yet complex force whose behavior is still not completely understood. Friction opposes relative motion between systems in contact, but also allows us to move. Friction arises in part due to the roughness of surfaces in contact. For one object to move along a surface, it must rise to where the peaks of the surface can skip along the bottom of the...
Contact Angle01:13

Contact Angle

When a solid is dipped inside a liquid, the liquid surface becomes curved near the contact. For some solid–liquid interfaces, the liquid is pulled up along the solid, while for others, the liquid surface is convex or depressed near the solid surface. This phenomenon can be explained using the concept of cohesive and adhesive forces.
The adhesive force is the molecular force between molecules of different materials, that is, between the molecules of the solid and the liquid. The cohesive force...
Impact01:30

Impact

Impact occurs when two bodies collide, leading to the application of impulsive forces between them. Analyzing impact mechanics involves considering two colliding particles moving along a line known as the line of impact, which passes through their centers and is perpendicular to the contact plane.
When particles with different initial velocities collide, they induce deformation by applying equal and opposite impulses. At the point of maximum deformation, the particles move together with...
Surface Tension01:24

Surface Tension

Surface tension is defined as the force per unit length (γ) acting along the surface of a liquid. It arises due to strong intermolecular forces of attraction. A molecule located inside the bulk of the liquid is surrounded by other molecules and experiences equal forces in all directions. However, a molecule at the surface experiences unbalanced forces because there are more neighboring molecules below than above. This creates a net inward force that pulls surface molecules toward the interior,...
Microbial Interactions: Mutualism01:25

Microbial Interactions: Mutualism

Mutualism is a symbiotic interaction in which all participating organisms benefit. These relationships can be obligate or facultative and are fundamental to ecosystem functions across diverse biological systems.Plant–Fungi MutualismOne well-known example is the association between plant roots and mycorrhizal fungi, such as Rhizophagus species. The fungal hyphae penetrate the root hairs and the epidermis, forming an extensive hyphal network that establishes a symbiotic association. Through this...

こちらも読む

関連記事

共著者、ジャーナル、引用グラフによってこの研究に関連する記事。

並び替え
Same author

A P2RY12 Deficiency Results in Sex-specific Cellular Perturbations and Sexually Dimorphic Behavioral Anomalies.

Research square·2024
Same author

Astrocytic β-catenin signaling via TCF7L2 regulates synapse development and social behavior.

Molecular psychiatry·2023
Same author

Microglia states and nomenclature: A field at its crossroads.

Neuron·2022
Same author

Differential Expression of CD49a and CD49b Determines Localization and Function of Tumor-Infiltrating CD8<sup>+</sup> T Cells.

Cancer immunology research·2021
Same author

Astrocyte development: A Guide for the Perplexed.

Glia·2015
Same author

Imaging microglia in brain slices and slice cultures.

Cold Spring Harbor protocols·2013
Same journal

A native sulfur deposit in Gale crater, Mars.

Science (New York, N.Y.)·2026
Same journal

Coordinated demise of harmful algal blooms.

Science (New York, N.Y.)·2026
Same journal

Genetic effects put into context.

Science (New York, N.Y.)·2026
Same journal

Bacteria share proteins to survive antibiotics.

Science (New York, N.Y.)·2026
Same journal

Impacts shaped Earth's first continents.

Science (New York, N.Y.)·2026
Same journal

Erratum for the Report "Covalently bonded single-molecule junctions with stable and reversible photoswitched conductivity" by C. Jia <i>et al</i>.

Science (New York, N.Y.)·2026
関連記事をすべて見る

関連する実験動画

Updated: May 7, 2026

Rapid and Refined CD11b Magnetic Isolation of Primary Microglia with Enhanced Purity and Versatility
07:54

Rapid and Refined CD11b Magnetic Isolation of Primary Microglia with Enhanced Purity and Versatility

Published on: April 13, 2017

9.8K

マイクログリアルシナプス相互作用の定義

Ukpong Eyo1, Anna Victoria Molofsky2

  • 1Center for Brain Immunology and Glia, Neuroscience Department, University of Virginia School of Medicine, Charlottesville, VA, USA.

Science (New York, N.Y.)
|September 14, 2023
PubMed
まとめ
この要約は機械生成です。

脳の免疫細胞であるマイクログリアは シナプスを切断するだけでなく この研究では 脳の健康と病気における 様々な機能について調べています

さらに関連する動画

Author Spotlight: Advancing Understanding Through Technological Innovations in Psychoneuroimmunology
07:41

Author Spotlight: Advancing Understanding Through Technological Innovations in Psychoneuroimmunology

Published on: May 31, 2024

1.2K
Author Spotlight: In Vitro Co-Culture Model for Studying Microglia-Neuronal Interactions in Disease Conditions
08:47

Author Spotlight: In Vitro Co-Culture Model for Studying Microglia-Neuronal Interactions in Disease Conditions

Published on: July 26, 2024

2.2K

関連する実験動画

Last Updated: May 7, 2026

Rapid and Refined CD11b Magnetic Isolation of Primary Microglia with Enhanced Purity and Versatility
07:54

Rapid and Refined CD11b Magnetic Isolation of Primary Microglia with Enhanced Purity and Versatility

Published on: April 13, 2017

9.8K
Author Spotlight: Advancing Understanding Through Technological Innovations in Psychoneuroimmunology
07:41

Author Spotlight: Advancing Understanding Through Technological Innovations in Psychoneuroimmunology

Published on: May 31, 2024

1.2K
Author Spotlight: In Vitro Co-Culture Model for Studying Microglia-Neuronal Interactions in Disease Conditions
08:47

Author Spotlight: In Vitro Co-Culture Model for Studying Microglia-Neuronal Interactions in Disease Conditions

Published on: July 26, 2024

2.2K

科学分野:

  • 神経科学
  • 免疫学
  • 細胞生物学

背景:

  • ミクログリアは中枢神経系に存在する主要な免疫細胞です.
  • 伝統的に,発達と可塑性中のシナプス剪定における彼らの役割は強調されています.

研究 の 目的:

  • 脳のマクロファージ (マイクログリア) の既知の機能を超えた多面的な役割を調査する.
  • 中枢神経系ホメオスタシスと病理学に対するマイクログリアのより広範な影響を強調する.

主な方法:

  • マイクログリア機能に関する既存の文献のレビュー.
  • 様々な神経学的モデルからの実験データ分析.
  • 脳の異なる状態におけるマイクログリアの行動に関する比較研究.

主要な成果:

  • マイクログリアは免疫監視,破片除去,神経栄養因子の放出に関与する.
  • 神経炎症や神経変性疾患に 関与しています
  • マイクログリアはニューロンの活動とネットワーク機能を活発に調節する.

結論:

  • マイクログリアは 脳の維持と修復に不可欠な 幅広い機能を備えています
  • これらの多様な役割を理解することは 神経学的疾患の新たな治療戦略の開発に不可欠です