アロマティック・デカルボキシラティブ・ハロスルフォニレーションによる非活性化酸とアミンの硫化物単体合成

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Updated: Jul 16, 2025

Preparation of N-2-alkoxyvinylsulfonamides from N-tosyl-1,2,3-triazoles and Subsequent Conversion to Substituted Phthalans and Phenethylamines
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Preparation of N-2-alkoxyvinylsulfonamides from N-tosyl-1,2,3-triazoles and Subsequent Conversion to Substituted Phthalans and Phenethylamines

Published on: January 3, 2018

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P Scott Pedersen1, David C Blakemore2, Gary M Chinigo2

  • 1Merck Center for Catalysis, Princeton University, Princeton, New Jersey 08544, United States.

Journal of the American Chemical Society
|September 20, 2023
PubMed
まとめ

この研究は,カルボキシル酸とアミンからスルフォナミドとスルフォニルフッ化物を合成するための新しい銅触媒法を導入しています. このアプローチは,事前機能化を回避し,様々な基板に適用でき,医薬品開発に役立ちます.

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