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Updated: Jul 16, 2025

A Reporter Based Cellular Assay for Monitoring Splicing Efficiency
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プロモーターRループはU2AF1をその相分離とRNA分割を調節するために採用する

Xiaomei He1, Jun Yuan2, Zi Gao1

  • 1Department of Chemistry, University of California Riverside, Riverside, California 92521-0403, United States.

Journal of the American Chemical Society
|September 21, 2023
PubMed
まとめ

スプライシングファクターU2AF1は,遺伝子プロモーターのRループとG4を結合し,RNAポリメラーゼIIの分布とmRNA前スプライシングに影響を与えます. この相互作用は,U2AF1の相分離を促進し,転写に影響を与える.

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