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Updated: Jul 16, 2025

A G-quadruplex DNA-affinity Approach for Purification of Enzymatically Active G4 Resolvase1
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A G-quadruplex DNA-affinity Approach for Purification of Enzymatically Active G4 Resolvase1

Published on: March 18, 2017

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G四重複RNAによるPRC2の不活性化のための構造的基礎

Jiarui Song1,2,3, Anne R Gooding1,2,3, Wayne O Hemphill1,2,3

  • 1Department of Biochemistry, University of Colorado Boulder, Boulder, CO 80303, USA.

Science (New York, N.Y.)
|September 21, 2023
PubMed
まとめ

ポリコンブ抑制複合体2 (PRC2) は,G-四重複合RNAを結合し,DNAの相互作用を阻害するダイマーを形成する. このRNA結合メカニズムは,PRC2の調節と遺伝子静止に関する新しい洞察を明らかにします.

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